SULT1E1 protein expression in Tumor and surrounding tissues
Expression of SULT1E1 protein in tumour was comparatively higher than corresponding surrounding tissues. A few surrounding tissue have shown an increased SULT1E1 expression, whose corresponding tumor shows more intense SULT1E1 expression. Our findings abide by earlier study that suggests that SULT1E1 is expressed more in the tumor tissues as compared to their surroundings, and our studydid the first attempt to explain that, though SULT1E1 is overexpressed in tumor it remains inactive (28). Considering both the studieswe utilized DAS and Chalcone separately as SULT1E1 inducer and reducing agent and also in combination to mainatian an elevated active SULT1E1 state.