‡ PK parameters between week 9-12 of
drug administration; #PK parameters between week 5-12 of drug
administration; Ctrough – plasma concentration at the
end of the dosing interval, Cmax – maximum plasma
concentration within the dosing interval, AUC0-inf –
area under the plasma plasma concentration time curve till infinity,AUC0-672 – area under the plasma plasma
concentration time curve within the last dosing interval period of 1
month (672 hrs), AUC0-1344 – area under the
plasma concentration time curve within the last dosing interval period
of 2 months (1344 hrs), SD – standard deviation.