Multifactorial logistic analysis of independent risk factors for
RSA
The factors independently associated with RSA in different groups are
shown in Table 3. In the overall population, TAFI, DD, and RDW-CV
variables were shown to be protective factors, all other variables were
considered risk factors. The regression analysis results showed that the
β-coefficient of plasma TAFI level was -0.04 [odds ratio (OR) 0.961;
95% CI, 0.936-0.987; P = 0.004].
In the Anti-TPO positive and Anti-TG positive populations, relatively
few factors were independently associated with RSA. In the Anti-TPO
positive group, TAFI (OR, 0.943; 95% CI, 0.896-0.992; P = 0.025],
LYMPH (OR. 1.034; 95% CI, 1.003-1.066; P =0.03), and LY30 (OR, 0.162;
95% CI, 0.035-0.738; P=0.019) were independent predictors of RSA. In
the Anti-TG positive group, TAFI (OR, 0.937; 95% CI, 0.884-0.992; P =
0.027), age (OR, 1.133; 95% CI, 1.057-1.215; P < 0.001), Fib
(OR, 0.593; 95% CI, 0.393-0.893; P = 0.012). FT3(OR,
2.205;95% CI, 1.307-3.722; P=0.003), and LY30(OR, 0.433;95% CI,
0.238-0.788; P=0.012) were independent predictors of RSA. In the
Anti-TPO negative group, TAFI (OR, 0.965; 95% CI, 0.935-0.996; P =
0.028), and age (OR, 1.067; 95% CI, 1.026-1.11; P = 0.001) were
independent predictors of RSA. It is worth noting that TAFI was shown to
be an independent protective factor for RSA in all four groups, except
in the Anti-TG negative group.