Materials & Methods
Following discussions with expert physicians, nurse specialists and
patients, an anonymous survey was performed to assess the real-world
patient experience of HAE and the early symptoms/signs of attacks. The
survey questionnaire was approved by HAE UK and the Asociación Española
De Angioedema Familiar (AEDAF), the local HAE patient organizations.
Invitations to participate containing a secure link to an on-line survey
were sent via e-mail to their membership databases. Informed consent was
obtained for all participants before accessing the survey.
In order to be eligible, patients had to be at least 16 years old,
diagnosed with HAE, taking
medication for HAE and to have previously experienced a prodromal sign
or symptom of an attack.
Data collection took place in February 2022 in the UK and May 2022 in
Spain and was analysed descriptively.