Materials & Methods
Following discussions with expert physicians, nurse specialists and patients, an anonymous survey was performed to assess the real-world patient experience of HAE and the early symptoms/signs of attacks. The survey questionnaire was approved by HAE UK and the Asociación Española De Angioedema Familiar (AEDAF), the local HAE patient organizations. Invitations to participate containing a secure link to an on-line survey were sent via e-mail to their membership databases. Informed consent was obtained for all participants before accessing the survey.
In order to be eligible, patients had to be at least 16 years old, diagnosed with HAE, taking medication for HAE and to have previously experienced a prodromal sign or symptom of an attack.
Data collection took place in February 2022 in the UK and May 2022 in Spain and was analysed descriptively.