5. Conclusion
Collectively, we pointed out the importance of M1 macrophage-centered
mutual interaction among immune cells in the fibrotic livers of
Mdr2-/- mice and indicated that, through this
rationale, PIC Ⅱ is a potential candidate for halting the progression of
liver fibrosis.
Conflicts of interest: The authors report no conflicts of
interest. The authors alone are responsible for the content and writing
of this article.