Figure 10 . (A ) Illustration of self-assembly behavior of DOX-loaded TPE-PLys-b -PMPC micelles, along with particle size distribution determined by DLS, the typical morphology of the polymer micelles detected by TEM, and CLSM images of DOX-loaded micelles after incubation with HeLa cells for 2, 4, 6, and 8 h. The DOX concentration is 10 µg/mL (scale bar in images was 10 µm). Reproduced with permission: Copyright 2017, Wiley-VCH.[149] (B ) Illustration of preparing TPE-TPA-DCM-loaded BSA NPs, along within vivo non-invasive fluorescence imaging of H22-tumorbearing mice after intravenous injection of TPE-TPA-DCM-loaded BSA NPs (with TPE-TPA-DCM loading of 0.86 wt%) (upper picture) and bare TPE-TPA-DCM NPs (lower picture) at same TPE-TPA-DCM concentration (white circles mark the tumor sites). Ex vivo fluorescence imaging on tumor tissue and major organs of mice treated with fluorogen-loaded BSA NPs, which were sacrificed at 24 h post-injection. Reproduced with permission: Copyright 2011, Wiley-VCH.[190] (C ) The pH-responsive AIE process assisted by the self-assembly of block copolymers. Reproduced with permission: Copyright 2021, Royal Society of Chemistry.[4]