Figure1. The neutralization potency and breath of 12-2A12. Figure1a showed the neutralizing activity of monoclonal antibody 12-2A12 against 59 street strains and CVS-N2C. Figure1b showed the neutralizing activity of monoclonal antibody 12-2A12 against virus strains isolated from different regions. First, the 59 street strains were classified according to the isolation region, and then the neutralizing activity of 12-2A12 against those strains in different regions was determined. Finally, the rank sum test was used to determine whether there was statistical difference in the neutralizing activity of 12-2A12 to the virus strains in the four regions.