REFERENCES
[1] FONT M D, THYAGARAJAN B, KHANNA A K. Sepsis and Septic Shock - Basics of diagnosis, pathophysiology and clinical decision making [J]. Med Clin North Am, 2020, 104(4): 573-85.
[2] FERNANDO S M, ROCHWERG B, SEELY A J E. Clinical implications of the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) [J]. Cmaj, 2018, 190(36): E1058-e9.
[3] HERNáNDEZ-QUILES R, MERINO-LUCAS E, BOIX V, et al. Bacteraemia and quick Sepsis Related Organ Failure Assessment (qSOFA) are independent risk factors for long-term mortality in very elderly patients with suspected infection: retrospective cohort study [J]. BMC Infect Dis, 2022, 22(1): 248.
[4] HALPERIN A V, DEL CASTILLO POLO J A, CORTES-CUEVAS J L, et al. Impact of Automated Blood Culture Systems on the Management of Bloodstream Infections: Results from a Crossover Diagnostic Clinical Trial [J]. Microbiol Spectr, 2022, 10(5): e0143622.
[5] AGNELLO L, GIGLIO R V, BIVONA G, et al. The Value of a Complete Blood Count (CBC) for Sepsis Diagnosis and Prognosis [J]. Diagnostics (Basel, Switzerland), 2021, 11(10).
[6] EVANS L, RHODES A, ALHAZZANI W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 [J]. Intensive Care Med, 2021, 47(11): 1181-247.
[7] GUARINO M, PERNA B, CESARO A E, et al. 2023 Update on Sepsis and Septic Shock in Adult Patients: Management in the Emergency Department [J]. J Clin Med, 2023, 12(9).
[8] DAMBROSO-ALTAFINI D, MENEGUCCI T C, COSTA B B, et al. Routine laboratory biomarkers used to predict Gram-positive or Gram-negative bacteria involved in bloodstream infections [J]. Sci Rep, 2022, 12(1): 15466.
[9] MATONO T, YOSHIDA M, KOGA H, et al. Diagnostic accuracy of quick SOFA score and inflammatory biomarkers for predicting community-onset bacteremia [J]. Sci Rep, 2022, 12(1): 11121.
[10] POOLMAN J T, WACKER M. Extraintestinal Pathogenic Escherichia coli, a Common Human Pathogen: Challenges for Vaccine Development and Progress in the Field [J]. J Infect Dis, 2016, 213(1): 6-13.
[11] FAY K, SAPIANO M R P, GOKHALE R, et al. Assessment of Health Care Exposures and Outcomes in Adult Patients With Sepsis and Septic Shock [J]. JAMA Netw Open, 2020, 3(7): e206004.
[12] BONTEN M, JOHNSON J R, VAN DEN BIGGELAAR A H J, et al. Epidemiology of Escherichia coli Bacteremia: A Systematic Literature Review [J]. Clin Infect Dis, 2021, 72(7): 1211-9.
[13] WU Y, WANG G, HUANG Z, et al. Diagnostic and therapeutic value of biomarkers in urosepsis [J]. Ther Adv Urol, 2023, 15: 17562872231151852.
[14] LIU L, FU Q, ZHANG D, et al. Analysis of Mean Corpuscular Volume and Red Cell Distribution Width in Patients with Aplastic Anemia [J]. Hemoglobin, 2023: 1-5.
[15] JAIN K, SHARMA D, PATIDAR M, et al. Red Cell Distribution Width as a Predictor of Mortality in Patients With Clinical Sepsis: Experience From a Single Rural Center in Central India [J]. Clin Pathol, 2022, 15: 2632010x221075592.
[16] DOGAN P, GUNEY VARAL I. Red cell distribution width as a predictor of late-onset Gram-negative sepsis [J]. Pediatr Int, 2020, 62(3): 341-6.
Table 1. Clinical baseline parameters of the blood culture positive and negative groups [median (P25-P75)]