A. Spike protein mutation sites of SARS-CoV-2 Prototype
(Genebank ID: MN908947), Omicron variants. BA.1 and BA.5. B.The IgG titers against S protein of SARS-Cov-2 prototype, Omicron
variants BA.1 and BA.5. The limitation of the detection (LOD) was1:400. The titers below the LOD were set to 200.C. The
neutralizing antibody titers against Prototype, and Omicron variants
BA.1 and BA.5 in individuals post the 3rd booster
vaccination within 2 months. The
limitation of the detection (LOD) was 1:10. The titers below the
LOD were set to 5.P -values were obtained by the unpaired t test,
*** P < 0.001, **** P < 0.0001, ns,
not significant.