Figure Legends
Fig. 1A. Peripheral blood film showing multiple rouleaux, morphologically normal WBC and platelets. May-Giemsa, x100 objective.
Fig. 1B. Bone marrow aspirate with numerous plasma cells, comprising over 90% of bone marrow cells, reduced erythopoiesis, granulopoiesis and thrombopoiesis. Plasma cells contain Dutcher bodies and Russell bodies. H&E, x200 objective.
Fig. 1C. Strong expression of CD138 on plasma cell surface. Clot section, H&E, x200 objective.
Fig. 2. Graphical changes over time in patient’s, hemoglobin, platelet counts, and affected free light chain over the course of disease and anti-myeloma therapy. Hb, Hemoglobin (g/L); Plt, platelet count (x109/L), FLC, serum free light chain (mg/L); MPV, Melphalan, Prednisone, Velcade (Bortezomib); Ld, Lenalidomide and dexamethasone; DVd, Daratumumab, Velcade (Bortezomib), dexamethasone; PCd, Pomalidomide, Cyclophosphamide, dexamethasone; Id, Ixazomib, dexamethasone.