Protein Average expression Occurence Available information Association to known genes/ proteins
Potential RNA/ ribosome-binding proteins Potential RNA/ ribosome-binding proteins Potential RNA/ ribosome-binding proteins Potential RNA/ ribosome-binding proteins Potential RNA/ ribosome-binding proteins
YqeY 16.09 Majority of bacteria may have tRNA amino acid amidase activity (COG) rpsU (operon)
YtpR 13.08 Bacilli, some Mollicutes tRNA-binding domain, interacts with GatB (IAX, O’Reilly), may participate in GatABC activity GatB (O’Reilly et al., 2023)
YabR
14.31
Many Firmicutes and few other bacteria
RNA-binding S1 domain, ribosome-interacting protein (O’Reilly), paralog of YugI
rcqP, divIC (operon) RcqU (O’Reilly et al., 2023)
YugI 14.13 Many Firmicutes and few other bacteria RNA-binding S1 domain, ribosome-interacting protein (O’Reilly), paralog of YabR Pgk, EzrA (O’Reilly et al., 2023)
YrzB
13.30
Many Firmicutes
Associated to the ribosome (IAX, O’Reilly)
RplR, RplT, RpmF, RpsN, RpsL (O’Reilly et al., 2023) reoM (operon)
YlxR 13.90 Widespread in bacteria, but not in beta- and gamma-Proteobacteria May bind to RNA (by similarity, Lamm-Schmidt et al., 2021) nusA, rplGA, infB, rbfA (operon)
KhpA 13.74 Widespread in bacteria, but not in alpha-, beta-, gamma-Proteobacteria KH domain, putative RNA-binding protein ffh, rpsP, rimM, trmD, rplS (operon)
YlbN
15.42
Most bacteria and plant chloroplasts
essential in plants, required for 23S rRNA accumulation
rpmF (operon) RpsJ (O’Reilly et al., 2023)
Potentially involved in the control of metabolism Potentially involved in the control of metabolism Potentially involved in the control of metabolism Potentially involved in the control of metabolism Potentially involved in the control of metabolism
YjlC 14.52 Some bacteria and archaea operon with ndh, and interaction with Ndh, may control Ndh activity Ndh (operon, O’Reilly et al., 2023)
YlaN 14.00 Many Bacilli Essential in the absence of iron, putative Fur effector Fur (O’Reilly et al., 2023)
YqhY 13.99 Many bacteria (not in proteobacteria) Asp23 family, paralog of YloU, conserved gene cluster with accBC, quasi-essential, may control fatty acid synthesis accB, accC (operon)
YloU 13.18 Many bacteria (not in proteobacteria) Asp23 family, paralog of YqhY, conserved gene cluster with fakA, may control fatty acid phosphorylation fakA (operon)
YneR
13.12
Bacilli
Interaction with PdhA and PdhB, inbits PDH activity (IAX, O’Reilly), renamed PdhI
PhdA, PdhB (O’Reilly et al., 2023) plsY (operon)
Potential regulatory elements Potential regulatory elements Potential regulatory elements Potential regulatory elements Potential regulatory elements
YtzK 14.32 B. subtilis May be regulatory element for tyrS expression acsA, tyrS (operon)
YpzE 13.12 B. subtilis Upstream of ribU, may control expression of ribU ribU (operon)
YwzH 13.76 Bacillus sp. First gene of the dlt operon for teichoic acid biosynthesis, microprotein, may control expression of the operon dltABCDE (operon)
YqzL 13.73 Bacillus sp. Microprotein cdd, era, recO (operon)
Other highly expressed unknown proteins Other highly expressed unknown proteins Other highly expressed unknown proteins Other highly expressed unknown proteins Other highly expressed unknown proteins
YkaA 13.50 Many bacteria and archaea Putative phosphate transport regulator (COG) pit (operon)
YjcF 13.49 Widespread in bacteria & euryarchaeota Predicted N-acyltransferase, GNAT family, operon with yjcH Pta, RplW (O’Reilly et al., 2023)
YjcH 13.43 Widespread in bacteria Operon with yjcF
YhaH 13.35 Widespread in bacteria, but not in alpha-, beta-, gamma-Proteobacteria Membrane protein, paralog of YtxH AccA (O’Reilly et al., 2023)
YtxH 13.99 Widespread in bacteria, but not in alpha-, beta-, gamma-Proteobacteria Paralog of YhaH brxC (operon)
YqgA 15.22 Closely related Bacillus species attached to cell wall, division sites
YybN 14.66 B. subtilis
YeeI 13.32 Nearly all bacteria Putative regulatory protein (COG)
YydD 13.24 Very few bacteria Low expression during sporulation
YhjA 13.80 Some Bacillus sp.
YpjP 13.43 Bacillus sp. Low expression during sporulation thyB, dfrA (operon)
YkuJ
14.01
Many Bacilli
Operon with ykuK, abbB, darB and ccpC
NusA (O’Reilly et al., 2023) abbB, darB, ccpC (operon)
YkuK 13.22 Many Bacilli Operon with ykuJ, abbB, darB and ccpC abbB, darB, ccpC (operon)
YocA 13.10 Most bacteria Membrane protein, glycoside hydrolase family 23 (UinProt)
YqkB 13.06 Many Bacilli Predicted Fe-S cluster biosynthesis protein (COG)
YneF 14.51 Most Bacilli and all Mollicutes Membrane protein, essential sirA (operon)
YubF 13.02 Bacillus sp. Membrane protein lytG (operon)
YfhC 13.03 Most bacteria and archaea Nitroreductase (COG)
YqxD 14.10 Many Firmicutes and Proteobacteria dnaG, sigA (operon)
YusG 14.09 Bacillus sp. gcvH (operon)
YaaK 13.95 Widespread in all bacteria Putative DNA-binding protein dnaX, recR, bofA (operon)
YhjA 13.80 Some Bacillus sp.
YlmG 13.88 Many bacteria Membrane protein, cytochrome maturation (COG) sepF (operon)
YaaR 13.55 Firmicutes, Spirochaetes, Thermotoga tmk, holB, trmN6 (operon)
YbzG 15.78 Very few Firmicutes part of ribosomal protein/ translation factor/ rpoA operon