Arbitrary expression levels as introduced in Nicolas et al. (2012)
were used. The number corresponds to logarithmical presentation of the
experimentally determined expression. To select this set of proteins,
we used two conditions: First, the average expression level under 104
conditions should be above 13. Second, the gene should be highly
expressed under all conditions. Exceptions were allowed for low
expression during sporulation. Proteins were regarded unknown if no
function had be identified prior to a large scale in vivointeraction study (O’Reilly et al., 2023). The list is also accessible
online
(http://www.subtiwiki.uni-goettingen.de/v4/category?id=SW.6.1).