\documentclass[10pt]{article}

\usepackage{fullpage}
\usepackage{setspace}
\usepackage{parskip}
\usepackage{titlesec}
\usepackage[section]{placeins}
\usepackage{xcolor}
\usepackage{breakcites}
\usepackage{lineno}
\usepackage{hyphenat}





\PassOptionsToPackage{hyphens}{url}
\usepackage[colorlinks = true,
            linkcolor = blue,
            urlcolor  = blue,
            citecolor = blue,
            anchorcolor = blue]{hyperref}
\usepackage{etoolbox}
\makeatletter
\patchcmd\@combinedblfloats{\box\@outputbox}{\unvbox\@outputbox}{}{%
  \errmessage{\noexpand\@combinedblfloats could not be patched}%
}%
\makeatother


\usepackage{natbib}




\renewenvironment{abstract}
  {{\bfseries\noindent{\abstractname}\par\nobreak}\footnotesize}
  {\bigskip}

\titlespacing{\section}{0pt}{*3}{*1}
\titlespacing{\subsection}{0pt}{*2}{*0.5}
\titlespacing{\subsubsection}{0pt}{*1.5}{0pt}


\usepackage{authblk}


\usepackage{graphicx}
\usepackage[space]{grffile}
\usepackage{latexsym}
\usepackage{textcomp}
\usepackage{longtable}
\usepackage{tabulary}
\usepackage{booktabs,array,multirow}
\usepackage{amsfonts,amsmath,amssymb}
\providecommand\citet{\cite}
\providecommand\citep{\cite}
\providecommand\citealt{\cite}
% You can conditionalize code for latexml or normal latex using this.
\newif\iflatexml\latexmlfalse
\providecommand{\tightlist}{\setlength{\itemsep}{0pt}\setlength{\parskip}{0pt}}%

\AtBeginDocument{\DeclareGraphicsExtensions{.pdf,.PDF,.eps,.EPS,.png,.PNG,.tif,.TIF,.jpg,.JPG,.jpeg,.JPEG}}

\usepackage[utf8]{inputenc}
\usepackage[english]{babel}



\usepackage{float}








\begin{document}

\title{Impact of inactive COVID-19 vaccination on the live birth and neonatal
outcomes of infertile couples with in vitro fertilization treatment}



\author[1]{xu yangying}%
\author[2]{Feng Yang}%
\author[1]{Duan Li}%
\author[1]{Wei Xue}%
\author[1]{Huimin Zhang}%
\author[1]{Yingxue Liu}%
\author[1]{Huaiqian Dou}%
\author[1]{Cuifang Hao}%
\affil[1]{Qingdao Women and Children's Hospital}%
\affil[2]{Qingdao Municipal Center for Disease Control and Prevention}%


\vspace{-1em}



  
  \date{May 17, 2024}


\begingroup
\let\center\flushleft
\let\endcenter\endflushleft
\maketitle
\endgroup





\selectlanguage{english}
\begin{abstract}
\textbf{Objective:} To assess the influence of vaccination on
reproductive outcome treatment of in vitro fertilization (IVF)
treatment. \textbf{Design:} A retrospective cohort study.
\textbf{Setting:} A university-affiliated reproductive medical center.
\textbf{Population:} The study included a total of 1105 couples who
underwent 1269~IVF treatment cycles with fresh cycles from March.1.2021
to January.1.2022. 215 vaccinated couples, 677 unvaccinated couples, 101
couples with female vaccinated only, and 112 couples with male
vaccinated only. \textbf{Methods:} 1105 couples were divided into four
groups according to the inactivated COVID-19 vaccination status of both
partners: Group A, both partners were vaccinated; Group B, only female
partners were vaccinated; Group C, only male partners were vaccinated;
Group D, neither of them was vaccinated. To compare the live birth and
neonatal outcomes among different vaccinated couples or unvaccinated
couples. \textbf{Main Outcome Measure(s):} The primary outcome was a
live birth rate and secondary outcomes were a low birth rate and preterm
birth rate. \textbf{Result(s):} The results showed that there are no
significant differences in live birth rate and neonatal outcomes among
different groups. The logistic regression model applied demonstrated
that the different vaccination statuses of infertile couples had no
effects on the live birth rates. \textbf{Conclusion(s):} The COVID-19
inactive vaccine did not affect the couples' reproductive outcome in IVF
treatment. To prevent serious complications related to COVID-19
infection during pregnancy and the perinatal period, active immunization
with vaccines is available before pregnancy.%
\end{abstract}%



\sloppy


\textbf{Hosted file}

\verb`manuscript.doc`  available at \url{https://authorea.com/users/580265/articles/621402-impact-of-inactive-covid-19-vaccination-on-the-live-birth-and-neonatal-outcomes-of-infertile-couples-with-in-vitro-fertilization-treatment}

\textbf{Hosted file}

\verb`Btable.doc`  available at \url{https://authorea.com/users/580265/articles/621402-impact-of-inactive-covid-19-vaccination-on-the-live-birth-and-neonatal-outcomes-of-infertile-couples-with-in-vitro-fertilization-treatment}

\selectlanguage{english}
\FloatBarrier
\end{document}

