Conclusion
Around 1 in 12 among the general population and 1 in 7 among all included populations were infected with HSV-2, which calls for more education to increase HSV-2 awareness and preventive intervention to curb the transmission of HSV-2. Regarding the language bias of HSV-2 epidemiology, it is necessary to include Chinese bibliographic databases in the reviewing scope to obtain a more comprehensive picture of HSV-2 infection for various populations and geographic regions and to extract these figures to reduce the language bias of this topic.