Conclusion
COVID-19 vaccination with COVISHILED and COVAXIN resulted in menstrual
cycle disturbances including changes in cycle length, duration, and
amount of bleeding and pre-and post-menstrual symptoms. Menstrual cycle
irregularities including length were significantly higher in the COVAXIN
group, whereas pre-and post-menstrual symptoms were more commonly
observed with the COVISHIELD vaccine. No significant difference was
observed in the incidence of COVID-19 infection in either group.
Furthermore, no significant association was found between COVID-19
infection and menstrual cycle changes. Hence, COVID-19 vaccines can
affect menstrual cycle patterns and lead to new-onset pre- and
post-menstrual symptoms in women, but for what duration these changes
will last post-vaccination need to be further evaluated.