I. ECG (12-Lead/Ambulatory) |
|
A. Spontaneous type 1 Brugada ECG pattern at nominal or high leads |
3.5 |
B. Fever-induced type 1 Brugada ECG pattern at nominal or high leads |
3 |
C. Type 2 or 3 Brugada ECG pattern that converts with provocative drug
challenge |
2 |
Only award points once for highest score within this category.
One item from this category must apply. |
*Only award points once
for highest score within this category. One item from this category must
apply. |
II. Clinical History* |
|
A. Unexplained cardiac arrest or documented VF/ polymorphic VT |
3 |
B. Nocturnal agonal respirations |
2 |
C. Suspected arrhythmic syncope |
2 |
D. Syncope of unclear mechanism/unclear etiology |
1 |
E. Atrial flutter/fibrillation in patients <30 years without
alternative etiology |
0.5 |
Only award points once for highest score within this category. |
*Only award points once for highest score within this
category. |
III. Family History |
|
A. First- or second-degree relative with definite BrS |
2 |
B. Suspicious SCD (fever, nocturnal, Brugada aggravating drugs) in a
first- or second-degree relative |
1 |
C. Unexplained SCD <45 years in first- or second- degree
relative with negative autopsy |
0.5 |
Only award points once for highest score within this category. |
*Only award points once for highest score within this
category.
|
IV. Genetic Test Result |
|
A. Probable pathogenic mutation in BrS susceptibility gene |
0.5 |
Score (requires at least 1 ECG finding) |
|
≥3.5 points: Probable/definite BrS |
|
2–3 points: Possible BrS |
|
<2 points: Non diagnostic |
|