2.2 Clinical data of the participants
All Patients’ data including age/sex, main symptoms, underlying diseases, sites of infection, causative fungus, CT/MR findings, individualized therapeutic schedule, following-up and the prognosis were listed in table1-3, Fig1-2, supplementary Fig1-4. Tissue sample for histopathological examination were collected during operation, swab sample for microbiological detection was taken from nose’s or eye’s secretions. Lesion scopes were mostly based on CT/MR findings. retrospective analyzed the treatment and prognosis of these cases, we shared our experience on management of AIFRS patients with cranio-facial-orbit involved.