Study subjects
In this study, 29,926 inhaled allergen sIgE test results were
retrospectively analyzed in Hunan Children’s Hospital from 2014 to 2021.
Inclusion criteria: (1) receiving serum inhaled allergen sIgE test; (2)
under 18 years old. Exclusion criteria: (1) lacking complete basic
personal information; (2) infected with COVID-19. The collected
information includes the patient’s name, gender, age, medical record
number, testing time, serum sIgE test items and results.
According to the time of COVID-19
outbreak, the subjects are divided into two groups: Before
COVID-19(January 1st, 2014.-January
31st, 2020), and During COVID-19 (after January
1st, 2020). They are divided into four age groups by
the developmental stage: infancy (<3 years old), preschool
(3-5 years old), school age (6-9 years old), and
adolescence (10-18 years old), as
well as spring (March-May), summer (June-August), autumn
(September-November), and winter (December-February) groups based on the
time of testing.
The examined allergens include: D. pteronyssinus (d1), D. farinae (d2),
dog hair (e2), cat hair (e1), cockroaches (i6), mulberry (T70), sycamore
pollen (sycamore), elm pollen (elm), grass pollen (u80), mugwort pollen
(w6), common ragweed pollen (w1), amaranth (w14), green oysters (f37),
mold (mx2). the testing of E1, elm, and sycamore began in November 2019.