logistics regression analysis
The positive rate of allergens was different in gender, age, and season (Table S2-S4 ). Table S5 -S7 respectively described the impact of the COVID-19 pandemic on allergen sensitization in subgroups by gender groups,age groups and season groups.
The positive rate of allergens was used as the dependent variable, and the time before and during COVID-19 was used as the independent variable. Multivariate regression analysis was conducted after adjusting gender, age and season. The results showed that the risk of d1, d2, mx2, e1, e2, w1, elm and w6 positive rates during COVID-19 was significantly higher than that before, with a statistical difference (d1(OR=1.174,95%CI=1.015~1.358 ),d2(OR=1.301,95%CI=1.093~1.549 ), e2(OR=1.499,95%CI=1.280~1.756 ), mx2(OR=3.959,95%CI=3.358~4.446 ), sycamore(OR=2.510,95%CI=1.522~4.139 ), e1(OR=249,95%CI=2.338~7.722 ), w1(OR=1.828, 95%CI=1.353~2.470 , elm(OR=3.576, 95%CI=1.425~8.974 ), w6(OR=1.538, 95%CI=1.123~2.106 ),u80(OR=2.521, 95%CI=1.413~4.497 )) (all P<0.05 ).