Study subjects
In this study, 29,926 inhaled allergen sIgE test results were retrospectively analyzed in Hunan Children’s Hospital from 2014 to 2021. Inclusion criteria: (1) receiving serum inhaled allergen sIgE test; (2) under 18 years old. Exclusion criteria: (1) lacking complete basic personal information; (2) infected with COVID-19. The collected information includes the patient’s name, gender, age, medical record number, testing time, serum sIgE test items and results. According to the time of COVID-19 outbreak, the subjects are divided into two groups: Before COVID-19(January 1st, 2014.-January 31st, 2020), and During COVID-19 (after January 1st, 2020). They are divided into four age groups by the developmental stage: infancy (<3 years old), preschool (3-5 years old), school age (6-9 years old), and adolescence (10-18 years old), as well as spring (March-May), summer (June-August), autumn (September-November), and winter (December-February) groups based on the time of testing.
The examined allergens include: D. pteronyssinus (d1), D. farinae (d2), dog hair (e2), cat hair (e1), cockroaches (i6), mulberry (T70), sycamore pollen (sycamore), elm pollen (elm), grass pollen (u80), mugwort pollen (w6), common ragweed pollen (w1), amaranth (w14), green oysters (f37), mold (mx2). the testing of E1, elm, and sycamore began in November 2019.