Impact of previous aborts/births on outcome
Despite treatment with LMWH and/or aspirin, 36 of the 60 women had two or three aborts prior to Anti-D treatment, and the remaining 24 had four or more aborts (figure 1). Following treatment with Anti-D, 27 women of the first group had successful pregnancies (75 %), nine had aborts (25 %), and three did not get pregnant (8 %). Of the second group of 24 women, 13 gave birth (54 %), nine had aborts (38 %), and three did not get pregnant (13 %).
Prior to treatment with Anti-D, 30 women had no birth, and 30 women had at least one birth (table 2). Of the first group, 22 women had successful pregnancies (73 %), eight had aborts (27 %), and one women did not get pregnant (3 %). Of the other 30 women, 18 women gave birth (60 %), ten had aborts (33 %), and five did not get pregnant (8 %) (table 2).
A chi-square test was used to compare number of aborts prior to treatment with Anti-D and successful pregnancy under treatment with Anti-D. No expected cell frequencies were below 5, and the results showed no significant correlation with χ²(1) = 0·303, p(χ²) = 0·582, p(Fisher’s exact test) = 0·784, V = 0·071.