Iron isotope compositions (δ⁵⁶Fe) of ferromanganese (Fe-Mn) crusts and nodules are reliable proxies for understanding the biogeochemical cycling of Fe in the ocean. Fe-Mn nodules/crusts are characterized by low δ⁵⁶Fe values (–0.8 to –0.05 ‰ IRMM 014), while the dissolved Fe in the deep ocean is ⁵⁶Fe enriched (d⁵⁶Fe range from +0.2 to +0.8 ‰). Here, we report Fe isotope compositions of top scrapings of sixteen Mn nodules and three Fe-Mn crusts and their geochemical compositions from the Central Indian Basin (CIB) to understand Fe isotope compositions. Based on their morphology and elemental compositions, the CIB nodules are divided into three groups: ‘hyrogenetic,’ ‘diagenetic,’ and ‘mixed’ types. The range of δ⁵⁶Fe values (-0.63 to -0.06 ‰) for CIB nodules and crusts is similar to those from different parts of the world ocean. The δ⁵⁶Fe values of the hydrogenetic group of CIB nodules are consistent with a fractionation model involving selective adsorption ⁵⁶Fe onto organic ligands (siderophore complexes). Using a fractionation factor of -0.77 ‰ between seawater and nodules, we estimate that δ⁵⁶Fe of the CIB deep seawater dissolved Fe range between +0.28 and +0.63 ‰ similar to the Atlantic deep seawater. The δ⁵⁶Fe values of mixed nodules correlate positively with Mn/Fe and concentrations of Mn, Cu, Zn, Mo, Cd, Sb, and Tl, and negatively with Fe, Be, Sc, Co, Zr, Nb, and rare earth elements (REE). These mixing lines attest to variable proportions of metals from diagenetic and hydrogenetic sources.