|
HR |
95% CI |
p value
|
|
HR |
95% CI |
p value
|
Male |
0.56 |
0.16-1.98 |
0.366 |
|
|
|
|
Age |
1.02 |
0.99-1.06 |
0.189 |
|
1.06 |
1.02-1.11 |
0.007 |
Body-mass index |
0.99 |
0.82-1.20 |
0.897 |
|
|
|
|
Smoking |
2.43 |
0.62-9.41 |
0.198 |
|
|
|
|
Alcoholism |
0.94 |
0.24-3.64 |
0.930 |
|
|
|
|
Co-morbidities |
|
|
|
|
|
|
|
Diabetes mellitus |
0.47 |
0.06-3.70 |
0.472 |
|
|
|
|
Hypertension |
1.67 |
0.43-6.45 |
0.459 |
|
|
|
|
Baseline eGFR (mL/min) |
1.02 |
1.00-1.04 |
0.047 |
|
1.04 |
1.02-1.06 |
<0.001 |
Mycobacterial study |
|
|
|
|
|
|
|
Positive acid-fast smear |
1.16 |
0.33-4.10 |
0.823 |
|
|
|
|
Culture-positive |
0.55 |
0.14-2.12 |
0.385 |
|
|
|
|
Side Effect
Baseline laboratory data
|
2.02
|
0.52-7.82
|
0.308
|
|
|
|
|
Blood urea nitrogen (mg/dL) |
1.01 |
0.93-1.10 |
0.769 |
|
|
|
|
Creatinine (mg/dL) |
0.04 |
0.001-1.46 |
0.080 |
|
|
|
|
Uric acid (mg/dL) |
0.66 |
0.43-1.02 |
0.063 |
|
|
|
|
Hemoglobin (g/dL) |
0.92 |
0.68-1.23 |
0.564 |
|
|
|
|
Platelet (K/μL) |
1.00 |
0.99-1.01 |
0.656 |
|
|
|
|
Leukocyte (K/μL) |
1.08 |
0.94-1.25 |
0.272 |
|
|
|
|
Eosinophil >350 (/μL) |
4.30 |
1.21-15.25 |
0.024 |
|
10.99 |
2.28-53.02 |
0.003 |
Alanine transaminase (U/L) |
1.004 |
0.98-1.03 |
0.777 |
|
|
|
|
Total bilirubin (mg/dL) |
2.66 |
0.73-9.73 |
0.139 |
|
|
|
|