Conclusions
We have delineated one aspect of the perinatal pathophysiology of
adenomyosis that can cause pain in more than one of eight pregnancies
with adenomyosis, which may be associated with an increased incidence of
PE resulting in preterm delivery. The risk of adverse perinatal outcomes
in a patient population with adenomyosis is not well known, but our
findings have provided new insights, indicating that those who develop
adenomyosis pain during pregnancy, especially those with high CRP
levels, may be at high risk for the later development of PE and
consequently warrant special attention in perinatal care.