Results
WIS was performed in 61 patients with drug-resistant TLE (68.9% were
male, median age 31, range 12–53). At the time of the EEG recordings,
the median disease course was 13 years (0.5–35 years). There were no
group differences in terms of age and sex between the TLE and HC groups
(Table 1). Forty-four patients presented with temporal lesions. Anterior
temporal lobectomy or lobotomy was performed on 50 patients. Pathology
reports were available for thirty-six patients, including focal cortex
dysplasia (n=28), hippocampal sclerosis (n=15), and tumors (n=3).
Radiofrequency thermocoagulation was performed in two patients, and
vagus nerve stimulation (VNS) was performed in one patient. Operations
were performed in more patients with cognitive impairment than in those
with normal cognition (p = 0.005). The mean IQ and memory
quotient (MQ) in the NC group was 107 (range 93-137) and 101 (range
72-122), respectively. In the AC group, the mean IQ was 71 (50–85) and
the mean MQ was 64 (40–83).