Variablea |
Successful (n=268) |
Failure (n=92) |
p-value |
Hemodynamically significant PDA: peri-extubation |
67 (25%) |
46 (50%) |
<0.001 |
GA (wks) |
27 (25-28) |
26 (24-27) |
<0.001 |
Birth Weight (gms) |
920 (770-1090) |
795 (690-914) |
<0.001 |
Highest RSS in first 6 hours |
3.60 (2.50-4.95) |
3.80 (2.58-6.15) |
0.045 |
Gender: Male |
129 (48%) |
47 (51%) |
0.63 |
Histologic chorioamnionitis |
124/253 (49%) |
53/84 (63%) |
0.03 |
Complete ANS Course |
168/266 (63%) |
59/91 (65%) |
0.77 |
Vaginal delivery |
84 (31%) |
28 (30%) |
0.87 |
Age at extubation (days) |
3 (2-10) |
4 (2-10) |
0.21 |
PMA at extubation (wks) |
28 (27-29) |
27 (26-28) |
<0.001 |
Weight at extubation (gms) |
960 (800-1090) |
815 (695-980) |
<0.001 |
Post extubation respiratory support (NIPPV/NCPAP vs
othersb) |
186 (69%) |
73 (80%) |
0.047 |
Caffeine use prior to extubation |
222 (83%) |
83 (90%) |
0.09 |
Pre-extubation VI |
5.88 (4.34-7.74) |
5.56 (4.43-8.00) |
0.83 |
Pre-extubation Fio2
|
23 (21-28) |
25 (21-30) |
0.001 |
Pre-extubation pH |
7.36 (7.30-7.41) |
7.34 (7.29-7.37) |
0.004 |