NO. |
TA-TMA diagnosis day post-HSCT |
Signs and symptoms |
With III-IV
GVHD |
Hb (g/L) |
PLT (10^9/L) |
PTR |
Proteinuria(+) |
Schistocytes |
LDH |
sC5b-9 |
Pathological examinations |
1 |
36 |
neurological
symptoms、hypertension、hematochezia、dyspnea、pericardial effusion |
No |
87 |
17 |
Yes |
3 |
+ |
912 |
- |
No thromboembolic |
2 |
46 |
hypertension、dyspnea、DAH |
No |
79 |
14 |
Yes |
0 |
- |
451 |
354 |
No thromboembolic |
3 |
94 |
neurological symptoms、hypertension、dyspnea |
Yes |
83 |
31 |
Yes |
1 |
- |
1174 |
- |
- |
4 |
94 |
hematuria、edema |
Yes |
60 |
75 |
No |
3 |
– |
367 |
439 |
No thromboembolic |
5 |
72 |
neurological symptoms、hypertension、mucocutaneous bleeding |
Yes |
80 |
34 |
Yes |
2 |
- |
679 |
245 |
thromboembolic |
6 |
7 |
neurological symptoms、hypertension、mucocutaneous
bleeding、hematochezia、ascites |
No |
123 |
32 |
Yes |
2 |
- |
1463 |
- |
- |
7 |
157 |
hypertension |
Yes |
78 |
62 |
No |
1 |
- |
660 |
329 |
thromboembolic |
8 |
13 |
neurological
symptoms、hypertension、hematochezia、hematuria、ascites |
No |
79 |
25 |
Yes |
2 |
- |
1516 |
- |
- |
9 |
121 |
neurological
symptoms、hypertension、mucocutaneous bleeding、dyspnea、pleural
effusion |
Yes |
79 |
17 |
Yes |
+- |
- |
761 |
421 |
thromboembolic |
10 |
111 |
hypertension、mucocutaneous bleeding |
No |
72 |
33 |
Yes |
+- |
- |
533 |
407 |
- |
11 |
43 |
hypertension、mucocutaneous bleeding |
No |
76 |
15 |
No |
0 |
- |
958 |
648 |
thromboembolic |
12 |
83 |
hypertension、dyspnea、pleural effusion |
No |
49 |
13 |
Yes |
2 |
- |
4034 |
410 |
No thromboembolic |
13 |
209 |
hypertension、dyspnea、hematochezia |
Yes |
72 |
34 |
Yes |
2 |
- |
696 |
- |
No thromboembolic |
14 |
178 |
hypertension、mucocutaneous bleeding、hematochezia |
Yes |
61 |
22 |
Yes |
0 |
- |
528 |
392 |
No thromboembolic |
15 |
289 |
hypertension、hematochezia |
Yes |
65 |
1 |
Yes |
2 |
- |
606 |
937 |
thromboembolic |
16 |
75 |
mucocutaneous bleeding |
No |
74 |
3 |
Yes |
2 |
- |
350 |
416 |
- |
17 |
56 |
hypertension、mucocutaneous bleeding |
No |
90 |
22 |
No |
1 |
+ |
734 |
358 |
- |
18 |
203 |
hypertension、mucocutaneous
bleeding、hematochezia、dyspnea、pleural effusion |
No |
41 |
15 |
Yes |
2 |
- |
1878 |
402.45 |
thromboembolic |
19 |
104 |
hypertension、mucocutaneous bleeding |
No |
89 |
47 |
Yes |
1 |
- |
837 |
203 |
- |
20 |
131 |
hypertension、mucocutaneous bleeding |
Yes |
75 |
28 |
Yes |
0 |
- |
599 |
651 |
thromboembolic |