CONCLUSIONS
The present meta-analysis suggests
using NIV-NAVA as a weaning mode may reduce extubation failure within
the first 72 hours for extremely premature infants.
With respect to the rates of BPD,
NEC, and ROP, there was not sufficient evidence that NIV-NAVA was
superior to conventional NIV. Preliminary research indicates that
NIV-NAVA has a promising future, but large randomized crossover studies
and long-term studies are yet to be conducted. Consequently, to assess
whether extubated to NIV-NAVA improve weaning success and clinical
outcomes after long-term intubation, further original RCTs and data are
needed.