Discussion
Principal findings
In this large, population-based linkage study of prenatal ultrasound
findings with kindergarten child development testing, we found that
estimated fetal weight percentiles were associated with child
development test results, with lower scores and increased risks of
developmental vulnerability among fetuses with lower EFW percentiles.
However, the charts’ value at predicting developmental vulnerability at
the individual level (i.e., discriminatory ability) was limited, as
evidenced by AUC of 53.0% for INTERGROWTH-21st;
52.8% for WHO and poor sensitivity across a range of cut-points.