Results
A total of 8,899 included AF patients with stage III CKD filled a new OAC prescription: 3,335 for warfarin, 744 for rivaroxaban 15 mg, 1,064 for rivaroxaban 20 mg, 1,674 for apixaban 2.5 mg, and 2,082 for apixaban 5.0 mg (Figure 1). The frequency of warfarin prescription decreased over time and was associated with a concomitant increase in DOAC prescription (Figure 2). In 2017, the most frequently initiated drug was apixaban 5.0 mg.