Sickle cell disease is the most prevalent inherited blood disorder in
the world, with significant morbidity and mortality. Patients often have
recurrent painful vaso-occlusive episodes, and the American Society of
Hematology gives a conditional recommendation for the use of regional
anesthesia for acute sickle cell pain management. This scoping review
summarizes the current evidence and identifies gaps for future research.
Our screening process is outlined, and articles that mentioned the use
of regional anesthesia for acute sickle cell crises were included. We
present and interpret our results and highlight opportunities for future
investigation.