Highlights
1. In epilepsy, the epigenetic regulation is involved in
epileptogenesis. We summarize the roles of histone modifications, DNA
methylation, ncRNAs and REST/NRSF in epilepsy.
2. MicroRNAs may be the biomarkers for the diagnosis of epilepsy and is
involved in treatment of epilepsy. LncRNAs may regulate epilepsy by
targeting microRNA. As one of the regulatory mechanisms of microRNAs,
m6A modification may be involved in the pathogenesis of epilepsy.
3. The mechanisms of epigenetic regulation in epilepsy may provide new
strategies for the treatment of epilepsy.