Statistical analysis
All statistical analyses were conducted using Excel and SPSS 26.0. Qualitative data were expressed as percentages (%), differences between groups were assessed by χ2 test, and Fisher’s exact test was used to test significance. Normally distributed data were expressed as the mean ± standard deviation, and differences between groups were analysed by one-way analysis of variance. Nonnormally distributed data were expressed as the median (minimum, maximum), and differences between groups were tested using the Mann–Whitney U test. Statistical significance was reached at P<0.05.