Introduction
Sarcoidosis is an inflammatory multisystem disease with unknown etiology characterized by the presence of non-caseating epithelioid cell granulomas in involved tissues [1].
Sarcoid-like reactions (SLR) are an autoinflammatory cause of mediastinal and hilar lymphadenopathy which can also affect other lymphadenopathy and organs but do not meet the diagnostic criteria for systemic sarcoidosis. [2]. This rare phenomenon has been reported primarily in patients with Hodgkin lymphoma or solid tumors (especially melanoma) receiving immunotherapy and chemotherapy. Cases of non-Hodgkin’s lymphoma (NHL) are extremely rare [2].
We report an uncommon case of SLR related to rituximab and affecting only the kidney in a patient who received chemotherapy with CHOP and rituximab for mantle cell lymphoma, a rare and aggressive form of NHL.