Introduction
Sarcoidosis is an inflammatory multisystem disease with unknown etiology
characterized by the presence of non-caseating epithelioid cell
granulomas in involved tissues [1].
Sarcoid-like reactions (SLR) are an autoinflammatory cause of
mediastinal and hilar lymphadenopathy which can also affect other
lymphadenopathy and organs but do not meet the diagnostic criteria for
systemic sarcoidosis. [2]. This rare phenomenon has been reported
primarily in patients with Hodgkin lymphoma or solid tumors (especially
melanoma) receiving immunotherapy and chemotherapy. Cases of
non-Hodgkin’s lymphoma (NHL) are extremely rare [2].
We report an uncommon case of SLR related to rituximab and affecting
only the kidney in a patient who received chemotherapy with CHOP and
rituximab for mantle cell lymphoma, a rare and aggressive form of NHL.