Variables
Control Group (n=48)
Sickle Cell Anemia Group (n=48)
p
Age, years 13 (10 -15) 13 (9 -15) 0.811
Height, cm 159 (140 -167) 147 (132 -158) 0.003
Weight, Kg 47 (35.7 -58.3) 37 (28 -51) 0.012
BMI, Kg/m2 19 (16.2 -21.8) 17 (15.5 -20.1) 0.086
Hb, g/Dl - 8 ± 1 -
Use of Hydroxyurea, n (%) - 34 (70.8%) -
FVC, L (%prev.) 3.3 ± 1.0 (104 ± 15) 2.4 ± 0.8 (92 ± 15) <0.001
FEV1, L (%prev.) 2.91 ± 0.9 (101 ± 13) 2.0 ± 0.6 (83 ± 15) <0.001
FEV1/FVC, % 90 ± 6 84 ± 8 <0.001
PEF, L (%prev.) 5.7 ± 1.8 (92 ± 18) 3.9 ± 1.3 (72 ± 22) <0.001
FEF25-75%, L (%prev.) 3.5 ± 1.2 (108 ± 22) 2.3 ± 0.7 (82 ± 22) <0.001
cm: centimeters; Kg: kilogram; Kg / m2: kilogram per square meter; BMI: body mass index; Hb: hemoglobin; g / dL: grams deciliters; FVC: forced vital capacity, L: liters; % pred: percentage of predicted; FEV1: forced expiratory volume in the first second; FEV1/FVC: ratio of forced expiratory volume in the first second divided by forced vital capacity; PEF: peak forced expiratory flow; FEF25-75%: forced expiratory flow 25-75 percent. cm: centimeters; Kg: kilogram; Kg / m2: kilogram per square meter; BMI: body mass index; Hb: hemoglobin; g / dL: grams deciliters; FVC: forced vital capacity, L: liters; % pred: percentage of predicted; FEV1: forced expiratory volume in the first second; FEV1/FVC: ratio of forced expiratory volume in the first second divided by forced vital capacity; PEF: peak forced expiratory flow; FEF25-75%: forced expiratory flow 25-75 percent. cm: centimeters; Kg: kilogram; Kg / m2: kilogram per square meter; BMI: body mass index; Hb: hemoglobin; g / dL: grams deciliters; FVC: forced vital capacity, L: liters; % pred: percentage of predicted; FEV1: forced expiratory volume in the first second; FEV1/FVC: ratio of forced expiratory volume in the first second divided by forced vital capacity; PEF: peak forced expiratory flow; FEF25-75%: forced expiratory flow 25-75 percent. cm: centimeters; Kg: kilogram; Kg / m2: kilogram per square meter; BMI: body mass index; Hb: hemoglobin; g / dL: grams deciliters; FVC: forced vital capacity, L: liters; % pred: percentage of predicted; FEV1: forced expiratory volume in the first second; FEV1/FVC: ratio of forced expiratory volume in the first second divided by forced vital capacity; PEF: peak forced expiratory flow; FEF25-75%: forced expiratory flow 25-75 percent.