AUTHOR CONTRIBUTIONS
The main structure of the article was developed after several discussions between the co-authors. Yun Wang and Peng Xie contributed equally to this work. Yun Wang and Peng Xie collected samples, conducted the laboratory assays, processed sequencing data, conducted statistical analysis, and wrote the manuscript. Jiyun She contributed to experimental concepts and design and trained and supervised Yun Wang and Peng Xie in designing experiments, analyzing data, and writing the manuscript. Yun Wang, Peng Xie, Aihua Deng, and Kerui Huang performed the experiments, and Shaogang Fan provided informative suggestions during the experimental design and revision of the article. All authors have read and approved the final manuscript.