3.9 Predictors of herb-drug interactions
According to the results of the multivariable logistic regression model,
the number of chemotherapeutic agents (OR: 1.92, 95% CI: 1.43–2.58;
P-value<0.0001), number of herbal medicines (OR: 1.15, 95%
CI: 1.06–1.24, P-value<0.0001), gastrointestinal cancers (OR:
0.08, 95% CI: 0.02–0.30, P-value<0.0001), thorax cancers
(OR: 0.10, 95% CI: 0.01–0.61, P-value= 0.01), IV clinical stage (OR:
8.42, 95% CI: 1.10–64.04, P-value= 0.04), unclear recurrence status
(OR: 0.06, 95% CI: 0.005–0.67, P-value= 0.02) and the experience of
pain during chemotherapy (OR=2.22, 95%CI:1.00–4.94; P-value=0.04) were
determined as the predictors of herb-drug interactions among cancer
patients (Table 4).