Introduction
Non steroidal anti-inflammatory drugs (NSAIDS) are very useful in management of pain and inflammation, thus constitute one of the widely used group of drugs in healthcare management.1,2Aceclofenac is a relatively new NSAID that exhibits preferential cyclooxygenase-2 inhibition and strong anti-inflammatory activity comparable to diclofenac.3
Stevens-Johnsons Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are potentially life threatening disorders that are usually induced by drugs. NSAIDs are one of the commonly implicated drug class in the causation of these severe cutaneous drug reactions.4But TEN with aceclofenac is rarely reported and to the best of our knowledge, there are only two reports of aceclofenac induced TEN in literature; one from Germany5 and one from India.6
Here, we report a case of aceclofenac induced TEN in a 58 year old female.