Introduction
Non steroidal anti-inflammatory drugs (NSAIDS) are very useful in
management of pain and inflammation, thus constitute one of the widely
used group of drugs in healthcare management.1,2Aceclofenac is a relatively new NSAID that exhibits preferential
cyclooxygenase-2 inhibition and strong anti-inflammatory activity
comparable to diclofenac.3
Stevens-Johnsons Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are
potentially life threatening disorders that are usually induced by
drugs. NSAIDs are one of the commonly implicated drug class in the
causation of these severe cutaneous drug reactions.4But TEN with aceclofenac is rarely reported and to the best of our
knowledge, there are only two reports of aceclofenac induced TEN in
literature; one from Germany5 and one from
India.6
Here, we report a case of aceclofenac induced TEN in a 58 year old
female.