Short term outcomes
Outcome data with respect to mortality, reintervention and complications post operatively are compared in Table 2 and Figure 1. A markedly lower mortality was observed in the aortic valve resuspension cohort at all time points during the follow up period. This difference was accounted for by the higher operative mortality observed in the ARR cohort (1.6% vs. 17%, p=0.003). The incidence of postoperative complications including return to theatre, stroke, renal failure, deep sternal wound infection and gastrointestinal bleeding was comparable in the two cohorts.
Multivariate logistic regression analysis found both root replacement (OR 35.2, 95% CI 2.4 – 522.0, p=0.01) and longer circulatory arrest time (OR 1.04, 95% CI 1.01 – 1.08, p=0.01) to be significantly associated with operative mortality (Table 3).
Data pertaining to the length of hospital stay was positively skewed. To assess the effects of pre-operative covariates on length of stay, an inverse gaussian generalised linear regression model was used, finding no association between patient/operative covariates and patient stay (p>0.05) (Table 4).