Chorea revealing celiac disease: cause or coincidence?
Mariem Mhiri 1, Anis
Hassine 2, R.ben Dhia1,
Salma Naija 2 ,Mouna Aissi 1,Sana BenAmor 2, Mahbouba
Frih-Ayed1
1Fattouma Bourguiba Hospital, neurology,
Monastir/Tunisia
2 Sahloul university hospital, neurology,
Sousse/Tunisia
Author correspondant: Mariem Mhiri
Tel: +21699115114
Mail: mariemmhiri@yahoo.com
Abstract
Introduction: A number of neurological disorders have been
reported to be associated with celiac disease including ataxia,
epilepsy, peripheral neuropathy and rarely chorea.
Case report: I reported the case of a patient aged 43 years
presents for choreic movements of brutal appearance. All the etiologic
report was negative except serology of celiac disease positive etiology
and gastric biopsy confirming the disease.
The evolution was marked by the disappearance of chorea following the
gluten-restricted diet.
Discussion: Despite the nature of association is unclear,
celiac disease may be a treatable cause of chorea.
Keyswords : Chorea, celiac disease, anti-gliadin antibodies.
Competing interests: No conflict of interest.
Introduction: The incidence of neurological in celiac disease
or associated with gluten-sensitivity without gastrointestinal
complaints was 10% (1). Cerebella ataxia and peripheral neuropathy was
considered to be the commonest neurological symptoms of gluten
sensitivity (2). But, these manifestations include epilepsy,
myoclonus,dementia, and some cases of chorea are described.
The onset of chorea in adulthood has many causes, such as metabolic,
genetic, and autoimmune factors. Huntington’s disease is the commonest
(3). Despite, a patient chorea free of family history of movement
disorders or dementia and association with autoimmune disease may
suggest diagnosis of celiac disease. It’s so easy when a patient has
gastrointestinal complaint. So, our patient is original case.