Discussion
A relationship between blood levels of Tacrolimus and an increasing thickness of left ventricular wall have been described more frequently with blood levels above 15 ng/mL, however it was also significant with blood levels between 10 and 15 ng/mL and below 10 ng/mL as in our case5. Also, these patients, usually present nonspecific symptoms such as asthenia, adynamia and lipothymia. However, a wide variety of signs and symptoms related with congestive heart failure as dyspnea, orthopnea, anorexia, fatigue, tachypnea, tachycardia, pulmonary edema and hepatomegaly have been described 8,12.