Study Characteristics
All the 14 records were
retrospective studies. 6716 advanced cancer patients
receiving ICIs treatment were
included. Among the14 studies, 3 studies were conducted in USA(22-24), 7
studies were conducted in Europe(25-31),1 study was conducted in
China(32), 3 studies were conducted worldwide(12, 33, 34). All the
studies provided the relationship between PPIs exposure and OS, 9 of
them offered the association between PPIs exposure and PFS. Table 1
summarized the basic information of the studies in this study. The NOS
score evaluating quality of included studies were also presented in
Table1.
Table 1 Study Characteristics in This Meta-analysis