Background:
Flow artifact, intrinsic to Magnetic Resonance Angiography (MRA), is
dependent on technical parameters and can lead to overinterpretation of
stenosis. Degree of cerebrovascular stenosis in pediatric patients with
sickle cell anemia (SCA) informs need for chronic transfusion therapy,
which may have significant risks. The primary objective of this study
was to document any change in stroke prevention therapy that could be
attributed to the implementation of a standardized MRA scanning
protocol.