Author Contributions
R.K. and C.J.C. developed the concept of this project. R.K. designed and
supervised experiments and advised in data analysis. K.G., C.J.C. and
R.K. wrote the manuscript. K.G., A.C.-R., S.L., D.R., P.D., A.C., and
A.M., collected and analyzed the data. K.G., A.C.-R., S.L., D.R.,
performed electrophysiological recordings. A.C. performed calcium
imaging experiments. S.P.-M performed docking studies of the compound.
H. and P.S.A. synthesized the compound. Y.L. and X.L. performed
behavioral experiments. P.D. and A.M. conducted biochemistry and
immunohistochemistry studies. U.S. developed the pharmacophore model and
performed the virtual screening. All authors had the opportunity to
discuss the results and comment on the manuscript.