I would like to submit our manuscript entitled “Pregnancy drug
use in Beijing district during 2016-2018: an analysis of data from
Beijing Prescription Evaluation System” for publication inBRITISH JOURNAL OF CLINICAL PHARMACOLOGY.We performed an analysis of prescriptions during pregnancy from Beijing
Prescription Comment System from 2016 to 2018. We extracted
prescriptions with key words from the system, and screened with specific
criteria, in order to summarize and evaluate the patterns and risk
factors associated to drugs during pregnancy. Ultimately, we included
647 varieties of chemical or biomedical drugs with 112,566
prescriptions. We performed data processing and statistical analyzes
using SPSS 22.0 and Graphpad 8.0 software.
Characteristics of prescriptions were evaluated through gestational age,
gestational week, prescribing year, prescribing departments. Potential
risk of drugs was assessed with FDA categorization, with pareto charts
of the drugs or departments. We also carried out multiple logistic
regression to explore the risk factors associated to drugs of C, D/X,
N/A categories. Finally, drug risk re-classification was performed with
Briggs categorization of medicine in B, C, D, N/A categories.
The paper described above is original work and has not been published
elsewhere, in whole or in part. None of the authors have any conflicts
of interests to report. We greatly appreciate your time to review our
manuscript and we look forward to hearing from you in due course.
Yours sincerely,
DU Boran
Corresponding author
FENG Xin
Email: fengxin1115@126.com