Data collection
The recording of demographic information, physical examination (including height, weight, and blood pressure), and head MRI were performed during a single interview. The following general information was obtained: age, sex, height, weight, body mass index (BMI), smoking (defined as having smoked >100 cigarettes in a lifetime), alcohol consumption (defined as consuming >30 g of alcohol per week for one year or longer), hypertension, diabetes, hyperlipidemia, stroke, coronary heart disease, myocardial infarction, and arrhythmia 19.