FEV1: forced expiratory volume in one second. BMI: Body
mass index. Exacerbations: incidence of exacerbations requiring OCS /
increase in maintenance OCS in the past 12 months before biologic
approval. AHE: acute healthcare encounters, which include Emergency
department/ hospital admissions. Multiple AHE: >1 AHE in
the past 12 months before biologic approval. mOCS: maintenance oral
corticosteroids. BMI: Body mass index. Obesity:
BMI≥30kgm-2. ICU: Intensive care unit. ACQ6: asthma
control questionnaire 6. AQLQ: Asthma Quality of Life Questionnaire.
HADS: hospital anxiety and depression scale. Adult onset: asthma age of
onset ≥18 years. Multiple logistic regression was performed (backward
variable selection) using baseline variables trending towards
significance (P<0.2). AUC: Area under the Receiver operating
characteristic curve.