Disease or Syndrome PIMs Medication risks use suggestion Incidence rate(cases)
A-level judgment standard A-level judgment standard A-level judgment standard A-level judgment standard
cardiovascular system
hypertension non-steroidal anti-inflammatory drugs retention of water and sodium, leading to high blood pressure Switch to acetaminophen or aspirin and monitoring blood pressure closely 34
Blood coagulation disorder or receiving anticoagulant therapy
Clopidogrel, non-steroidal anti-inflammatory drugs
Increase the risk of bleeding Prolong clotting time or inhibit platelet aggregation, increase the potential risk of bleeding Use with caution, Adopt non-drug therapy, switch to paracetamol, and combine with gastric mucosal protective agent
39
urinary system
Renal insufficiency Non-steroidal anti-inflammatory drugs retention of water and sodium, aggravating or causing kidney failure Avoid using 7
Endocrine System
Osteoporosis glucocorticoids Accelerate bone loss Use with caution 2
diabetes Glucocorticoids (long-term use) Exacerbate diabetes Take inhaled corticosteroids and closely monitor blood sugar 8