Altered methylation levels of the 9 aging-related genes in peripheral blood of asthma patients
As the mRNA expression of the 9 aging-related genes altered significantly in asthma patients, we further determined the methylation levels of the 9 aging-related genes in asthma patients. We analyzed the total 856 CpG sites in the CpG islands of the 9 aging-related genes. The methylation analysis result was showed via volcano maps (Figure 2). It is showed that the methylation levels of 68 CpG sites were related to asthma at FDR < 5%. The detailed information of all the differential 68 DMSs were demonstrated in Table S1.