Conclusion
Nasal irrigation is a potential route to administer drugs into the sinus
in unoperated CRS
patients. Patients with phenotyping of moderate to high severity disease
of sinuses and the CRSsNP might benefit from having drugs delivered into
the sinus via nasal irrigation. However, the alternative technique is
not superior to using nasal spray at the most challenging anatomical
areas, i.e., the frontal and sphenoid sinuses.