Conclusion
As the most remarkable therapeutic property of celery is BP reduction,
it was important to figure out the safety evaluation of celery in humans
as herbal medicine. In this study, celery seed capsules (1.34g extract
per day) were given to patients as drug supplements in a randomized,
triple-blind, placebo-controlled, cross-over clinical trial. The results
indicated that the celery seed capsule not only is safe for hypertensive
patients but also caused a reduction in BP values, improved kidney and
liver function, FBS, and lipid profile, which are statistically and
clinically significant and were in normal ranges. However, no
significant change was observed in blood cells and serum electrolytes.
According to the promising results of this clinical trial, celery seed
extract can be considered a safe supplement for hypertensive patients.