Introduction:
An atrial septal aneurysm (ASA) is an uncommon but well-known structural
saccular malformation of the atrial septum that bulges into the right or
left atrium without clinical significance [1]. This lesion is
commonly associated with congenital heart diseases such as patent
foramen ovale, atrial septal defect, mitral valve prolapse, tricuspid
valve prolapse, Marfan syndrome, sinus of Valsalva aneurysm, and aortic
dissection. However, it may be caused by acquired heart disease
[2,3]. It is usually asymptomatic with clinical, cardiologic, and
electrocardiographic examinations failing to reveal its presence
[3]. Only a few examples of atrial septal aneurysms have been
described in connection with cerebral embolism; either from a
paradoxical embolism of venous thrombi through a right to left shunt or
passage of a thrombus formed on the left atrial side of the aneurysm
with atrial fibrillation [1,2]. The following report summarizes
cryptogenic stroke in an adult Sudanese female with an interatrial
septal aneurysm.