Treatment-Related Adverse Events
Treatment-related adverse events are summarized in Table 4. Sixteen patients (39%) experienced Grade 3-5 treatment-related complications. Grade 3-4 myelosuppression occurred in five patients. Nine patients experienced Grade 3-5 infections, which included four episodes of sepsis, three episodes of pneumonia, one episode of mucositis and one post-surgical infection of unknown origin. One patient experienced post-surgical cardiopulmonary failure and one experienced moyamoya following RT. Of the 16 patients, nine received combined chemotherapy/RT, four received chemotherapy only, one received RT only and two underwent surgery without adjuvant therapy. Of the 16 patients who experienced adverse events, eight (50%) died of their complications.