Treatment-Related Adverse Events
Treatment-related adverse events are summarized in Table 4. Sixteen
patients (39%) experienced Grade 3-5 treatment-related complications.
Grade 3-4 myelosuppression occurred in five patients. Nine patients
experienced Grade 3-5 infections, which included four episodes of
sepsis, three episodes of pneumonia, one episode of mucositis and one
post-surgical infection of unknown origin. One patient experienced
post-surgical cardiopulmonary failure and one experienced moyamoya
following RT. Of the 16 patients, nine received combined
chemotherapy/RT, four received chemotherapy only, one received RT only
and two underwent surgery without adjuvant therapy. Of the 16 patients
who experienced adverse events, eight (50%) died of their
complications.